Berberine in Malaria. A Preliminary Note
نویسنده
چکیده
tj ^Kopra (1933) has pointed out that berbenne, .^J^active principle of berberine-containing plants, has some remarkable properties in its behaviour towards the parasites of malaria. Its sulphate has been found to liberate the parasites into the peripheral circulation from the internal organs, so that, whereas blood films taken before the administration of berberine are negative, those taken after it become positive. Sabatini (1928) used it as a provocative agent in the diagnosis of latent malaria. Its action resembles what Chopra and Das Gupta (1928) observed in the case of pentavalent organic antimonials which when injected intravenously have the remarkable properties of expelling Leishmania donovani from the internal organs to the peripheral circulation. Perez Andre (1927) advocated berberine in the treatment of malarial splenomegaly. This property of berberine was, however, not taken advantage of in the treatment of malaria acting, as it does, as a powerful agent in helping quinine to attack the parasites. Quinine lias
منابع مشابه
Berberine Protects Against murine malaria-Induced Spleen Tissue Damage
Malaria is one of the most severe public health problems worldwide. Here, we investigated the ameliorative role of berberine against Plasmodium chabaudi-induced spleen injury. Mice were divided into 3 groups. The first group served as a vehicle control, the second group was infected with 10 P. chabaudi infected erythrocytes and the third group was infected with P. chabaudi then treated with 10 ...
متن کاملStability and Numerical Analysis of Malaria- mTB- HIV/AIDS Co-infection (TECHNICAL NOTE)
In this paper, we develop a mathematical model to examine the transmission dynamics of curable malaria, curable mTB and non-curable HIV/AIDS and their co-infection. The size of population has been taken as varying due to the emigration of susceptible population. The total population is divided into five subclasses as susceptible, malaria infected, mTB infected, HIV infection and AIDS by assumin...
متن کاملA New Approach in Preliminary Design of Closed Loop Solar Thermal Systems (RESEARCH NOTE)
In this paper, a model for closed loop solar system is presented and an attempt is made to generalize the model to be utilized for primary design of any solar active thermal system. This model may be used for systems in which gas or a liquid are fluids that flow. Two new parameters, namely, the system heat delivery factor and the system heat absorption factor are introduced in the model. These ...
متن کاملEffect of Berberine on the Levels of Sex Hormones in Polycystic Ovary Syndrome-Induced by Letrozole in Adult Female Wistar Rats
Background and Objectives: Berberine is a yellow alkaloid, which is found in root, rhizome, skin, and stem of many plants, including barberry, turmeric, and poppy. Berberine has anti-inflammatory, anti-bacterial, and anti-viral properties. In the present study, the protective effect of berberine on letrozole-induced Polycystic Ovary Syndrome (PCOS), was investigated in adult female Wistar rats....
متن کامل